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CD16 PE Antibody
產品型號:Cat #: 55-816LB
簡介:


Clone 3G8, Mouse IgG1,k
100 Tests/Unit
Brand: Caprico Biotechnologies
Monoclonal antibody specific to human and non-human primate CD16
The 3G8 antibody has been reported for use i

CD16 PE Antibody  的詳細介紹

The clone 3G8, a mouse monoclonal antibody, binds to the 50-65 kDa transmembrane protein of IgG Fc?RIII known as CD16, a surface antigen commonly associated with human NK cells. In addition to surface expression on NK cells, CD16 is expressed on activated monocytes, macrophages, neutrophils, and placental trophoblasts in humans. 3G8 binds either with the aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell mediated cytotoxicity (ADCC). Diseases associated with CD16 dysfunction include immunodeficiency 20 and systemic lupus erythematosus.

Each lot of these antibodies has been pre-titrated and tested by flow cytometric analysis of human PBMCs such that 0.5μg (unconjugated, Biotin) or 5μl (conjugated) of these products are sufficient for staining 1 million cells in a 100μl staining volume or 100μl of whole blood. It is recommended to titrate antibody reactivity empirically for optimal performance. Non-human primate cross-reactivity has been validated using the APC conjugated clone 3G8 product. Do you need an antibody for an antigen you don't see on our website? Do you need a different conjugation than what we have listed? We have a wide selection of antigens with a variety of conjugations available. Please reach out to us at [email protected].

Conjugation PE
Excitation Laser Blue (488nm)
Reactivity Human, Rhesus, Cynomolgus monkey, Baboon
Host Mouse
Antigen CD16
Clone 3G8
Isotype IgG1,k
Status RUO
Size 100 Tests/Unit
Storage 2-8°C and protected from prolonged exposure to light
Formulation PBS pH 7.2, 0.2% BSA (w/v), 0.09% sodium azide
Immunogen Human peripheral blood T lymphocytes
Clonality Monoclonal


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